Multidisciplinary Management of Acinar Cell Carcinoma of the Parotid Gland with Free Flap Reconstruction A case report

Abstract

Background: Acinic cell carcinoma (AciCC) is a rare malignancy of the salivary glands, primarily affecting the parotid gland. It is a low-grade tumor with an indolent course and a favorable prognosis. Despite its slow progression, early diagnosis and appropriate treatment are essential for optimal outcomes.

Case Summary: We present a case of a 56-year-old male with a five-year history of a progressively enlarging ulceroproliferative growth on the right cheek. Imaging and histopathological examination confirmed AciCC of the parotid gland. The patient underwent neoadjuvant chemotherapy with Paclitaxel and Carboplatin, followed by wide local excision, right modified radical neck dissection, and reconstruction using a left free radial forearm flap with split-thickness skin grafting. The postoperative period was uneventful, and the patient showed no recurrence during follow-up.

Conclusion: This case highlights the importance of a multidisciplinary approach, integrating chemotherapy, surgery, and reconstruction, to achieve successful oncologic and functional outcomes in AciCC of the parotid gland.

Keywords: Acinic cell carcinoma (AciCC), Salivary gland tumors, Parotid gland, Low-grade carcinoma

Source of support: Nil.

Conflict of interest: None