Effect of Topical Insulin on Diabetic Foot Ulcers

Seema  Khanna; Gaurav  Yadav; Mohan  Kumar; SK  Singh

Journal Issue

Journal of Surgery Archives
View Current Issue

News

Posted on : 29 April 2022

Journal of Surgery Archives is a double blind peer-review Journal with the aim to provide a synergized approach of engagement among the researchers from Indian region and worldwide.

Highly Accessed

Journal of Surgery Archives

Keywords

General Surgery

Critical care

Endocrine Surgery

Bariatric surgery

Surgical Oncology

Minimal Invasive Surgery

Minimal Access Surgery

Journal History

The idea for bringing this journal is to engage local, national, and international researchers from surgery specialties on a common platform. This effort will help all stakeholders with equal aplomb. The institute is glad to introduce the journal for the same purpose.

Review Process

Journal of Surgery Archives employs double-blind peer review process before reaching to the selection, which means the identity of the author and reviewer is kept confidential and vice versa.

PDF

Published: Oct 20, 2023

Keywords:

Diabetic foot ulcers, Topical insulin, VEGF, MIP-2

Seema Khanna

Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India

Gaurav Yadav

Department of General, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India

Mohan Kumar

Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India

SK Singh

Department of Endocrinology and Metabolism, Banaras Hindu University, Varanasi, Uttar Pradesh, India

Abstract

Diabetic foot ulcers developing in a patient with long standing diabetes is a cause of morbidity and amputation in many patients. Our understanding of non healing of these ulcers at cellular and molecular levels needs to expand, to enable us to develop efficacious and cost effective therapeutic regimens
Methods: The effect of topical insulin on diabetic foot ulcers was studied over a period of 2 years in a single surgical unit.
Conclusion: Topical Insulin was found to be beneficial in chronic wound healing and it’s role on neutrophil function and neo angiogenesis evaluated by measurement of MIP-2 and VEGF levels.

How to Cite

Khanna, S. ., Yadav, G. ., Kumar, M. ., & Singh, S. . (2023). Effect of Topical Insulin on Diabetic Foot Ulcers. Journal of Surgery Archives, 1(01), 24–28. Retrieved from https://jsurgarchives.com/index.php/ijsa/article/view/79